Macrophage Colony-Stimulating Factor Augments Tie2-Expressing Monocyte Differentiation, Angiogenic Function, and Recruitment in a Mouse Model of Breast Cancer

Reports demonstrate the role of M-CSF (CSF1) in tumor progression in mouse models as well as the prognostic value of macrophage numbers in breast cancer patients. Recently, a subset of CD14+ monocytes expressing the Tie2 receptor, once thought to be predominantly expressed on endothelial cells, has...

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Autors principals: Forget, Mary A., Voorhees, Jeffrey L., Cole, Sara L., Dakhlallah, Duaa, Patterson, Ivory L., Gross, Amy C., Moldovan, Leni, Mo, Xiaokui, Evans, Randall, Marsh, Clay B., Eubank, Tim D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043882/
https://ncbi.nlm.nih.gov/pubmed/24892425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098623
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