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Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories

Stem and progenitor cell fate transitions constitute key decision points in organismal development that enable access to a developmental path or actively preclude others. Using the hematopoietic system, we analyzed the relative importance of cell fate–promoting mechanisms versus negating fate-suppre...

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Pubblicato in:J Exp Med
Autori principali: Johnson, Kirby D., Conn, Daniel J., Shishkova, Evgenia, Katsumura, Koichi R., Liu, Peng, Shen, Siqi, Ranheim, Erik A., Kraus, Sean G., Wang, Weixin, Calvo, Katherine R., Hsu, Amy P., Holland, Steven M., Coon, Joshua J., Keles, Sunduz, Bresnick, Emery H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Rockefeller University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596813/
https://ncbi.nlm.nih.gov/pubmed/32736380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191526
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