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Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories

Stem and progenitor cell fate transitions constitute key decision points in organismal development that enable access to a developmental path or actively preclude others. Using the hematopoietic system, we analyzed the relative importance of cell fate–promoting mechanisms versus negating fate-suppre...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Johnson, Kirby D., Conn, Daniel J., Shishkova, Evgenia, Katsumura, Koichi R., Liu, Peng, Shen, Siqi, Ranheim, Erik A., Kraus, Sean G., Wang, Weixin, Calvo, Katherine R., Hsu, Amy P., Holland, Steven M., Coon, Joshua J., Keles, Sunduz, Bresnick, Emery H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596813/
https://ncbi.nlm.nih.gov/pubmed/32736380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191526
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