Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories

Stem and progenitor cell fate transitions constitute key decision points in organismal development that enable access to a developmental path or actively preclude others. Using the hematopoietic system, we analyzed the relative importance of cell fate–promoting mechanisms versus negating fate-suppre...

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Dades bibliogràfiques
Publicat a:J Exp Med
Autors principals: Johnson, Kirby D., Conn, Daniel J., Shishkova, Evgenia, Katsumura, Koichi R., Liu, Peng, Shen, Siqi, Ranheim, Erik A., Kraus, Sean G., Wang, Weixin, Calvo, Katherine R., Hsu, Amy P., Holland, Steven M., Coon, Joshua J., Keles, Sunduz, Bresnick, Emery H.
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7596813/
https://ncbi.nlm.nih.gov/pubmed/32736380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20191526
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