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Prediction of Serum HIV-1 Neutralization Titers After Passive Administration of VRC01
BACKGROUND: VRC01 is a human IgG1 broadly neutralizing antibody (bnAb) that binds to the HIV-1 envelope glycoprotein. It is being evaluated in two ongoing efficacy trials, the first assessment of a passively-administered bnAb for HIV-1 prevention. HVTN 104 was a Phase 1 trial of VRC01. SETTING: We m...
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| Publié dans: | J Acquir Immune Defic Syndr |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7594341/ https://ncbi.nlm.nih.gov/pubmed/31855881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002272 |
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