Population Analysis of Staphylococcus aureus Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia

Staphylococcal superantigens (SAgs) are a family of secreted toxins that stimulate T cell activation and are associated with an array of diseases in humans and livestock. Most SAgs produced by Staphylococcus aureus are encoded by mobile genetic elements, such as pathogenicity islands, bacteriophages...

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Pubblicato in:mBio
Autori principali: Vrieling, Manouk, Tuffs, Stephen W., Yebra, Gonzalo, van Smoorenburg, Marleen Y., Alves, Joana, Pickering, Amy C., Park, Joo Youn, Park, Nogi, Heinrichs, David E., Benedictus, Lindert, Connelley, Timothy, Seo, Keun Seok, McCormick, John K., Fitzgerald, J. Ross
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593966/
https://ncbi.nlm.nih.gov/pubmed/33109757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02082-20
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