Manipulation of Innate and Adaptive Immunity by Staphylococcal Superantigens

Staphylococcal superantigens (SAgs) constitute a family of potent exotoxins secreted by Staphylococcus aureus and other select staphylococcal species. SAgs function to cross-link major histocompatibility complex (MHC) class II molecules with T cell receptors (TCRs) to stimulate the uncontrolled acti...

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Bibliographic Details
Published in:Pathogens
Main Authors: Tuffs, Stephen W., Haeryfar, S. M. Mansour, McCormick, John K.
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6027230/
https://ncbi.nlm.nih.gov/pubmed/29843476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens7020053
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