Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells

The globally prominent pathogen Streptococcus pyogenes secretes potent immunomodulatory proteins known as superantigens (SAgs), which engage lateral surfaces of major histocompatibility class II molecules and T-cell receptor (TCR) β-chain variable domains (Vβs). These interactions result in the acti...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Zeppa, Joseph J., Kasper, Katherine J., Mohorovic, Ivor, Mazzuca, Delfina M., Haeryfar, S. M. Mansour, McCormick, John K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5617250/
https://ncbi.nlm.nih.gov/pubmed/28794279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700858114
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