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Nasopharyngeal infection by Streptococcus pyogenes requires superantigen-responsive Vβ-specific T cells
The globally prominent pathogen Streptococcus pyogenes secretes potent immunomodulatory proteins known as superantigens (SAgs), which engage lateral surfaces of major histocompatibility class II molecules and T-cell receptor (TCR) β-chain variable domains (Vβs). These interactions result in the acti...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5617250/ https://ncbi.nlm.nih.gov/pubmed/28794279 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700858114 |
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