Attenuation of massive cytokine response to the staphylococcal enterotoxin B superantigen by the innate immunomodulatory protein lactoferrin

Staphylococcal enterotoxin B (SEB) is a pyrogenic exotoxin and a potent superantigen which causes massive T cell activation and cytokine secretion, leading to profound immunosuppression and morbidity. The inhibition of SEB-induced responses is thus considered a goal in the management of certain type...

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Detalhes bibliográficos
Main Authors: Hayworth, J L, Kasper, K J, Leon-Ponte, M, Herfst, C A, Yue, D, Brintnell, W C, Mazzuca, D M, Heinrichs, D E, Cairns, E, Madrenas, J, Hoskin, D W, McCormick, J K, Haeryfar, S M M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Translational Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710593/
https://ncbi.nlm.nih.gov/pubmed/19659771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2009.03963.x
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