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The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

Bacterial superantigens (SAgs) cause Vβ-dependent T-cell proliferation leading to immune dysregulation associated with the pathogenesis of life-threatening infections such as toxic shock syndrome, and necrotizing pneumonia. Previously, we demonstrated that staphylococcal enterotoxin-like toxin X (SE...

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Publicado en:PLoS Pathog
Autores principales: Tuffs, Stephen W., James, David B. A., Bestebroer, Jovanka, Richards, Amy C., Goncheva, Mariya I., O’Shea, Marie, Wee, Bryan A., Seo, Keun Seok, Schlievert, Patrick M., Lengeling, Andreas, van Strijp, Jos A., Torres, Victor J., Fitzgerald, J. Ross
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589267/
https://ncbi.nlm.nih.gov/pubmed/28880920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006461
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