The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

Bacterial superantigens (SAgs) cause Vβ-dependent T-cell proliferation leading to immune dysregulation associated with the pathogenesis of life-threatening infections such as toxic shock syndrome, and necrotizing pneumonia. Previously, we demonstrated that staphylococcal enterotoxin-like toxin X (SE...

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Publicat a:PLoS Pathog
Autors principals: Tuffs, Stephen W., James, David B. A., Bestebroer, Jovanka, Richards, Amy C., Goncheva, Mariya I., O’Shea, Marie, Wee, Bryan A., Seo, Keun Seok, Schlievert, Patrick M., Lengeling, Andreas, van Strijp, Jos A., Torres, Victor J., Fitzgerald, J. Ross
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589267/
https://ncbi.nlm.nih.gov/pubmed/28880920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006461
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