The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

Bacterial superantigens (SAgs) cause Vβ-dependent T-cell proliferation leading to immune dysregulation associated with the pathogenesis of life-threatening infections such as toxic shock syndrome, and necrotizing pneumonia. Previously, we demonstrated that staphylococcal enterotoxin-like toxin X (SE...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Tuffs, Stephen W., James, David B. A., Bestebroer, Jovanka, Richards, Amy C., Goncheva, Mariya I., O’Shea, Marie, Wee, Bryan A., Seo, Keun Seok, Schlievert, Patrick M., Lengeling, Andreas, van Strijp, Jos A., Torres, Victor J., Fitzgerald, J. Ross
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589267/
https://ncbi.nlm.nih.gov/pubmed/28880920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006461
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