The Staphylococcus aureus superantigen SElX is a bifunctional toxin that inhibits neutrophil function

Bacterial superantigens (SAgs) cause Vβ-dependent T-cell proliferation leading to immune dysregulation associated with the pathogenesis of life-threatening infections such as toxic shock syndrome, and necrotizing pneumonia. Previously, we demonstrated that staphylococcal enterotoxin-like toxin X (SE...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Tuffs, Stephen W., James, David B. A., Bestebroer, Jovanka, Richards, Amy C., Goncheva, Mariya I., O’Shea, Marie, Wee, Bryan A., Seo, Keun Seok, Schlievert, Patrick M., Lengeling, Andreas, van Strijp, Jos A., Torres, Victor J., Fitzgerald, J. Ross
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5589267/
https://ncbi.nlm.nih.gov/pubmed/28880920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006461
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