Population Analysis of Staphylococcus aureus Reveals a Cryptic, Highly Prevalent Superantigen SElW That Contributes to the Pathogenesis of Bacteremia

Staphylococcal superantigens (SAgs) are a family of secreted toxins that stimulate T cell activation and are associated with an array of diseases in humans and livestock. Most SAgs produced by Staphylococcus aureus are encoded by mobile genetic elements, such as pathogenicity islands, bacteriophages...

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Bibliografiske detaljer
Udgivet i:mBio
Main Authors: Vrieling, Manouk, Tuffs, Stephen W., Yebra, Gonzalo, van Smoorenburg, Marleen Y., Alves, Joana, Pickering, Amy C., Park, Joo Youn, Park, Nogi, Heinrichs, David E., Benedictus, Lindert, Connelley, Timothy, Seo, Keun Seok, McCormick, John K., Fitzgerald, J. Ross
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593966/
https://ncbi.nlm.nih.gov/pubmed/33109757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02082-20
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