RNA-binding protein Ptbp1 regulates alternative splicing and transcriptome in spermatogonia and maintains spermatogenesis in concert with Nanos3

PTBP1, a well-conserved RNA-binding protein, regulates cellular development by tuning posttranscriptional mRNA modification such as alternative splicing (AS) or mRNA stabilization. We previously revealed that the loss of Ptbp1 in spermatogonia causes the dysregulation of spermatogenesis, but the mol...

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Detalles Bibliográficos
Publicado en:J Reprod Dev
Main Authors: SENOO, Manami, HOZOJI, Hiroshi, ISHIKAWA-YAMAUCHI, Yu, TAKIJIRI, Takashi, OHTA, Sho, UKAI, Tomoyo, KABATA, Mio, YAMAMOTO, Takuya, YAMADA, Yasuhiro, IKAWA, Masahito, OZAWA, Manabu
Formato: Artigo
Idioma:Inglês
Publicado: The Society for Reproduction and Development 2020
Assuntos:
Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593632/
https://ncbi.nlm.nih.gov/pubmed/32624547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2020-060
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