The HIV-1 latent reservoir is largely sensitive to circulating T cells

HIV-1-specific CD8+ T cells are an important component of HIV-1 curative strategies. Viral variants in the HIV-1 reservoir may limit the capacity of T cells to detect and clear virus-infected cells. We investigated the patterns of T cell escape variants in the replication-competent reservoir of 25 p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Warren, Joanna A, Zhou, Shuntai, Xu, Yinyan, Moeser, Matthew J, MacMillan, Daniel R, Council, Olivia, Kirchherr, Jennifer, Sung, Julia M, Roan, Nadia R, Adimora, Adaora A, Joseph, Sarah, Kuruc, JoAnn D, Gay, Cynthia L, Margolis, David M, Archin, Nancie, Brumme, Zabrina L, Swanstrom, Ronald, Goonetilleke, Nilu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2020
Pynciau:
Immunology and Inflammation
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7593086/
https://ncbi.nlm.nih.gov/pubmed/33021198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57246
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