GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

Neuropathic pain is a debilitating public health concern for which novel non-narcotic therapeutic targets are desperately needed. Using unbiased transcriptomic screening of the dorsal horn spinal cord after nerve injury we have identified that Gpr183 (Epstein-Barr virus–induced gene 2) is upregulate...

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Udgivet i:J Pharmacol Exp Ther
Main Authors: Braden, Kathryn, Giancotti, Luigino Antonio, Chen, Zhoumou, DeLeon, Chelsea, Latzo, Nick, Boehm, Terri, D’Cunha, Napoleon, Thompson, Bonne M., Doyle, Timothy M., McDonald, Jeffrey G., Walker, John K., Kolar, Grant R., Arnatt, Christopher Kent, Salvemini, Daniela
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2020
Fag:
Drug Discovery and Translational Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592849/
https://ncbi.nlm.nih.gov/pubmed/32913007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000105
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