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P2Y(14) Receptor Antagonists Reverse Chronic Neuropathic Pain in a Mouse Model
[Image: see text] Eight P2Y(14)R antagonists, including three newly synthesized analogues, containing a naphthalene or phenyl-triazolyl scaffold were compared in a mouse model of chronic neuropathic pain (sciatic constriction). P2Y(14)R antagonists rapidly (≤30 min) reversed mechano-allodynia, with...
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| Publicado en: | ACS Med Chem Lett |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Chemical
Society
2020
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7294700/ https://ncbi.nlm.nih.gov/pubmed/32551012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00115 |
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