GPR183-Oxysterol Axis in Spinal Cord Contributes to Neuropathic Pain

Neuropathic pain is a debilitating public health concern for which novel non-narcotic therapeutic targets are desperately needed. Using unbiased transcriptomic screening of the dorsal horn spinal cord after nerve injury we have identified that Gpr183 (Epstein-Barr virus–induced gene 2) is upregulate...

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Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Braden, Kathryn, Giancotti, Luigino Antonio, Chen, Zhoumou, DeLeon, Chelsea, Latzo, Nick, Boehm, Terri, D’Cunha, Napoleon, Thompson, Bonne M., Doyle, Timothy M., McDonald, Jeffrey G., Walker, John K., Kolar, Grant R., Arnatt, Christopher Kent, Salvemini, Daniela
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2020
Subjects:
Drug Discovery and Translational Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592849/
https://ncbi.nlm.nih.gov/pubmed/32913007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000105
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