GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents

Treating neuropathic pain is challenging and novel non–opioid-based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence, and in situ hybridization, we found that the expression of the orphan GPCR Gpr160 and GPR160 increased in the rodent dorsal horn of the s...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Yosten, Gina L.C., Harada, Caron M., Haddock, Chris, Giancotti, Luigino Antonio, Kolar, Grant R., Patel, Ryan, Guo, Chun, Chen, Zhoumou, Zhang, Jinsong, Doyle, Timothy M., Dickenson, Anthony H., Samson, Willis K., Salvemini, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Concise Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190928/
https://ncbi.nlm.nih.gov/pubmed/31999650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133270
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