GPR160 de-orphanization reveals critical roles in neuropathic pain in rodents

Treating neuropathic pain is challenging and novel non–opioid-based medicines are needed. Using unbiased receptomics, transcriptomic analyses, immunofluorescence, and in situ hybridization, we found that the expression of the orphan GPCR Gpr160 and GPR160 increased in the rodent dorsal horn of the s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Clin Invest
Päätekijät: Yosten, Gina L.C., Harada, Caron M., Haddock, Chris, Giancotti, Luigino Antonio, Kolar, Grant R., Patel, Ryan, Guo, Chun, Chen, Zhoumou, Zhang, Jinsong, Doyle, Timothy M., Dickenson, Anthony H., Samson, Willis K., Salvemini, Daniela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2020
Aiheet:
Concise Communication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190928/
https://ncbi.nlm.nih.gov/pubmed/31999650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI133270
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia