Phase 2 Study of Pembrolizumab and Circulating Biomarkers to Predict Anticancer Response in Advanced, Unresectable Hepatocellular Carcinoma

BACKGROUND: Checkpoint inhibitors have shown modest activity in patients with advanced hepatocellular carcinoma (HCC). Herein, the authors report a prospective single-institution clinical/translational phase 2 study of pembrolizumab in patients with advanced HCC and circulating biomarkers closely re...

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Gepubliceerd in:Cancer
Hoofdauteurs: Feun, Lynn G., Li, Ying-Ying, Wu, Chunjing, Wangpaichitr, Medhi, Jones, Patricia D., Richman, Stephen P., Madrazo, Beatrice, Kwon, Deukwoo, Garcia-Buitrago, Monica, Martin, Paul, Hosein, Peter J., Savaraj, Niramol
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592647/
https://ncbi.nlm.nih.gov/pubmed/31251403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.32339
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