Developing Genome-wide Polygenic Risk Scores for Coronary Artery Disease in South Asians

BACKGROUND: Genome-wide polygenic scores (GPS) integrate information from many common DNA variants into a single number. Because rates of coronary artery disease (CAD) are substantially higher among South Asians, a GPS to identify high-risk individuals may be particularly useful in this population....

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Publicado no:J Am Coll Cardiol
Principais autores: Wang, Minxian, Menon, Ramesh, Mishra, Sanghamitra, Patel, Aniruddh P., Chaffin, Mark, Tanneeru, Deepak, Deshmukh, Manjari, Mathew, Oshin, Apte, Sanika, Devanboo, Christina S, Sundaram, Sumathi, Samson, Praveena L, Murugan, Sakthivel, Sharma, Krishna Kumar, Karthikeyan, R, Santhosh, Sam, Thachathodiyl, Rajesh, Ahamed, Hisham, Balegadde, Aniketh Vijay, Alexander, Thomas, Swaminathan, Krishnan, Gupta, Rajeev, Mullasari, Ajit S, Sigamani, Alben, Kanchi, Muralidhar, Peterson, Andrew S., Butterworth, Adam S, Danesh, John, Angelantonio, Emanuele Di, Naheed, Aliya, Inouye, Michael, Chowdhury, Rajiv, Ramprasad, Vedam L, Kathiresan, Sekar, Gupta, Ravi, Khera, Amit V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592606/
https://ncbi.nlm.nih.gov/pubmed/32762905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2020.06.024
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