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Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling

Infarct expansion can occur after myocardial infarction (MI), which leads to adverse left ventricular (LV) remodeling and failure. An imbalance between matrix metalloproteinase (MMP) induction and tissue inhibitors of MMPs (TIMPs) can accelerate this process. Past studies have shown different biolog...

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Podrobná bibliografie
Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Lobb, David C., Doviak, Heather, Brower, Gregory L., Romito, Eva, O’Neill, Jason W., Smith, Stephen, Shuman, James A., Freels, Parker D., Zellars, Kia N., Freeburg, Lisa A., Khakoo, Aarif Y., Lee, TaeWeon, Spinale, Francis G.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589956/
https://ncbi.nlm.nih.gov/pubmed/32958629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000047
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