Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling

Infarct expansion can occur after myocardial infarction (MI), which leads to adverse left ventricular (LV) remodeling and failure. An imbalance between matrix metalloproteinase (MMP) induction and tissue inhibitors of MMPs (TIMPs) can accelerate this process. Past studies have shown different biolog...

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Publicado en:J Pharmacol Exp Ther
Autores principales: Lobb, David C., Doviak, Heather, Brower, Gregory L., Romito, Eva, O’Neill, Jason W., Smith, Stephen, Shuman, James A., Freels, Parker D., Zellars, Kia N., Freeburg, Lisa A., Khakoo, Aarif Y., Lee, TaeWeon, Spinale, Francis G.
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2020
Materias:
Cardiovascular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589956/
https://ncbi.nlm.nih.gov/pubmed/32958629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000047
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