Targeted Injection of a Truncated Form of Tissue Inhibitor of Metalloproteinase 3 Alters Post–Myocardial Infarction Remodeling

Infarct expansion can occur after myocardial infarction (MI), which leads to adverse left ventricular (LV) remodeling and failure. An imbalance between matrix metalloproteinase (MMP) induction and tissue inhibitors of MMPs (TIMPs) can accelerate this process. Past studies have shown different biolog...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Lobb, David C., Doviak, Heather, Brower, Gregory L., Romito, Eva, O’Neill, Jason W., Smith, Stephen, Shuman, James A., Freels, Parker D., Zellars, Kia N., Freeburg, Lisa A., Khakoo, Aarif Y., Lee, TaeWeon, Spinale, Francis G.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2020
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589956/
https://ncbi.nlm.nih.gov/pubmed/32958629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.120.000047
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