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Intracoronary delivery of recombinant TIMP-3 after myocardial infarction: effects on myocardial remodeling and function

Ischemia-reperfusion (IR) and myocardial infarction (MI) cause adverse left ventricular (LV) remodeling and heart failure and are facilitated by an imbalance in matrix metalloproteinase (MMP) activation and the endogenous tissue inhibitors of metalloproteinase (TIMPs). We have identified that myocar...

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Publicat a:Am J Physiol Heart Circ Physiol
Autors principals: Barlow, Shayne C., Doviak, Heather, Jacobs, Julia, Freeburg, Lisa A., Perreault, Paige E., Zellars, Kia N., Moreau, Karen, Villacreses, Camila F., Smith, Stephen, Khakoo, Aarif Y., Lee, TaeWeon, Spinale, Francis G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5668606/
https://ncbi.nlm.nih.gov/pubmed/28754718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00114.2017
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