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Endoglin Promotes Myofibroblast Differentiation and Extracellular Matrix Production in Diabetic Nephropathy

Diabetic nephropathy (DN) is a complication of diabetes mellitus that can lead to proteinuria and a progressive decline in renal function. Endoglin, a co-receptor of TGF-β, is known primarily for regulating endothelial cell function; however, endoglin is also associated with hepatic, cardiac, and in...

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Pubblicato in:Int J Mol Sci
Autori principali: Gerrits, Tessa, Zandbergen, Malu, Wolterbeek, Ron, Bruijn, Jan A., Baelde, Hans J., Scharpfenecker, Marion
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589772/
https://ncbi.nlm.nih.gov/pubmed/33081058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207713
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