Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation

Myofibroblasts, the primary effector cells that mediate matrix remodeling during pulmonary fibrosis, rapidly assemble an extracellular fibronectin matrix. Tensin (TNS) 1 is a key component of specialized cellular adhesions (fibrillar adhesions) that bind to extracellular fibronectin fibrils. We hypo...

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Bibliografiska uppgifter
I publikationen:Am J Respir Cell Mol Biol
Huvudupphovsmän: Bernau, Ksenija, Torr, Elizabeth E., Evans, Michael D., Aoki, Jason K., Ngam, Caitlyn R., Sandbo, Nathan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Thoracic Society 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5449508/
https://ncbi.nlm.nih.gov/pubmed/28005397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0104OC
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