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Tensin 1 Is Essential for Myofibroblast Differentiation and Extracellular Matrix Formation
Myofibroblasts, the primary effector cells that mediate matrix remodeling during pulmonary fibrosis, rapidly assemble an extracellular fibronectin matrix. Tensin (TNS) 1 is a key component of specialized cellular adhesions (fibrillar adhesions) that bind to extracellular fibronectin fibrils. We hypo...
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| Pubblicato in: | Am J Respir Cell Mol Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Thoracic Society
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5449508/ https://ncbi.nlm.nih.gov/pubmed/28005397 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0104OC |
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