Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis

BACKGROUND: Fibrosing disorders of the lung, such as idiopathic pulmonary fibrosis, are characterized by progressive extracellular matrix accumulation that is driven by myofibroblasts. The transcription factor megakaryoblastic leukemia-1 (MKL1) mediates myofibroblast differentiation in response to s...

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Dettagli Bibliografici
Pubblicato in:Respir Res
Autori principali: Bernau, Ksenija, Ngam, Caitlyn, Torr, Elizabeth E, Acton, Benjamin, Kach, Jacob, Dulin, Nickolai O, Sandbo, Nathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392778/
https://ncbi.nlm.nih.gov/pubmed/25885656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-015-0206-6
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