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Glomerular clusterin expression is increased in diabetic nephropathy and protects against oxidative stress-induced apoptosis in podocytes

Clusterin, a glycoprotein encoded by the CLU gene, is expressed in many tissues, including the kidney, and clusterin expression is upregulated in the glomeruli of patients with various forms of kidney disease. Here, we investigated the role of clusterin in diabetic nephropathy (DN). In this study, w...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: He, Junling, Dijkstra, Kyra L., Bakker, Kim, Bus, Pascal, Bruijn, Jan A., Scharpfenecker, Marion, Baelde, Hans J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484791/
https://ncbi.nlm.nih.gov/pubmed/32913257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-71629-z
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