Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel

KEY POINTS: 25‐Hydroxyvitamin D (25OHD) is a partial agonist of TRPV1 whereby 25OHD can weakly activate TRPV1 yet antagonize the stimulatory effects of the full TRPV1 agonists capsaicin and oleoyl dopamine. 25OHD binds to TRPV1 within the same vanilloid binding pocket as capsaicin. 25OHD inhibits th...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Physiol
मुख्य लेखकों: Long, Wentong, Fatehi, Mohammad, Soni, Shubham, Panigrahi, Rashmi, Philippaert, Koenraad, Yu, Yi, Kelly, Rees, Boonen, Brett, Barr, Amy, Golec, Dominic, Campbell, Scott A., Ondrusova, Katarina, Hubert, Matt, Baldwin, Troy, Lemieux, M. Joanne, Light, Peter E.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2020
विषय:
Molecular and Cellular
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7589233/
https://ncbi.nlm.nih.gov/pubmed/32721035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP279961
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