Cardiac Late Sodium Channel Current Is a Molecular Target for the Sodium/Glucose Cotransporter 2 Inhibitor Empagliflozin

BACKGROUND: SGLT2 (sodium/glucose cotransporter 2) inhibitors exert robust cardioprotective effects against heart failure in patients with diabetes, and there is intense interest to identify the underlying molecular mechanisms that afford this protection. Because the induction of the late component...

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Detalhes bibliográficos
Publicado no:Circulation
Main Authors: Philippaert, Koenraad, Kalyaanamoorthy, Subha, Fatehi, Mohammad, Long, Wentong, Soni, Shubham, Byrne, Nikole J., Barr, Amy, Singh, Jyoti, Wong, Jordan, Palechuk, Taylor, Schneider, Chloe, Darwesh, Ahmed M., Maayah, Zaid H., Seubert, John M., Barakat, Khaled, Dyck, Jason R.B., Light, Peter E.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2021
Assuntos:
Original Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8154177/
https://ncbi.nlm.nih.gov/pubmed/33832341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.121.053350
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