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Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Soluplus(®) Polymeric Micelles Encapsulating Fenbendazole
Fenbendazole (FEN), a broad-spectrum benzimidazole anthelmintic, suppresses cancer cell growth through various mechanisms but has low solubility and achieves low blood concentrations, which leads to low bioavailability. Solubilizing agents are required to prepare poorly soluble drugs for injections;...
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| 出版年: | Pharmaceutics |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589096/ https://ncbi.nlm.nih.gov/pubmed/33096915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12101000 |
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