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Evaluation of the Physicochemical Properties, Pharmacokinetics, and In Vitro Anticancer Effects of Docetaxel and Osthol Encapsulated in Methoxy Poly(ethylene glycol)-b-Poly(caprolactone) Polymeric Micelles

Docetaxel (DTX), a taxane-based anticancer drug, and osthol (OTH), a coumarin-derivative compound, have shown anticancer effects against different types of cancers through various mechanisms. However, these drugs have low solubility in water and low oral bioavailability, and thus their clinical appl...

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Podrobná bibliografie
Vydáno v:Int J Mol Sci
Hlavní autoři: Jo, Min Jeong, Lee, Yu Jin, Park, Chun-Woong, Chung, Youn Bok, Kim, Jin-Seok, Lee, Mi Kyeong, Shin, Dae Hwan
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7794789/
https://ncbi.nlm.nih.gov/pubmed/33379376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010231
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