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Physicochemical, Pharmacokinetic, and Toxicity Evaluation of Soluplus(®) Polymeric Micelles Encapsulating Fenbendazole
Fenbendazole (FEN), a broad-spectrum benzimidazole anthelmintic, suppresses cancer cell growth through various mechanisms but has low solubility and achieves low blood concentrations, which leads to low bioavailability. Solubilizing agents are required to prepare poorly soluble drugs for injections;...
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| Publicado no: | Pharmaceutics |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7589096/ https://ncbi.nlm.nih.gov/pubmed/33096915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12101000 |
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