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Molecular Basis for Polyketide Ketoreductase–Substrate Interactions

Polyketides are a large class of structurally and functionally diverse natural products with important bioactivities. Many polyketides are synthesized by reducing type II polyketide synthases (PKSs), containing transiently interacting standalone enzymes. During synthesis, ketoreductase (KR) catalyze...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Zhao, Shiji, Ni, Fanglue, Qiu, Tianyin, Wolff, Jacob T., Tsai, Shiou-Chuan, Luo, Ray
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588967/
https://ncbi.nlm.nih.gov/pubmed/33066287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21207562
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