Structural basis of αE-catenin–F-actin catch bond behavior

Cell-cell and cell-matrix junctions transmit mechanical forces during tissue morphogenesis and homeostasis. α-Catenin links cell-cell adhesion complexes to the actin cytoskeleton, and mechanical load strengthens its binding to F-actin in a direction-sensitive manner. Specifically, optical trap exper...

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Опубликовано в: :eLife
Главные авторы: Xu, Xiao-Ping, Pokutta, Sabine, Torres, Megan, Swift, Mark F, Hanein, Dorit, Volkmann, Niels, Weis, William I
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2020
Предметы:
Structural Biology and Molecular Biophysics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
https://ncbi.nlm.nih.gov/pubmed/32915141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60878
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