αE-catenin actin-binding domain alters actin filament conformation and regulates binding of nucleation and disassembly factors

The actin-binding protein αE-catenin may contribute to transitions between cell migration and cell–cell adhesion that depend on remodeling the actin cytoskeleton, but the underlying mechanisms are unknown. We show that the αE-catenin actin-binding domain (ABD) binds cooperatively to individual actin...

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Hauptverfasser: Hansen, Scott D., Kwiatkowski, Adam V., Ouyang, Chung-Yueh, Liu, HongJun, Pokutta, Sabine, Watkins, Simon C., Volkmann, Niels, Hanein, Dorit, Weis, William I., Mullins, R. Dyche, Nelson, W. James
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2013
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3842997/
https://ncbi.nlm.nih.gov/pubmed/24068324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-07-0388
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