Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains

The role of mutations in genes associated with phenotypic resistance to bedaquiline (BDQ) and delamanid (DLM) in Mycobacterium tuberculosis complex (MTBc) strains is poorly characterized. A clear understanding of the genetic variants’ role is crucial to guide the development of molecular-based drug...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Microbiol
Auteurs principaux: Battaglia, S., Spitaleri, A., Cabibbe, A. M., Meehan, C. J., Utpatel, C., Ismail, N., Tahseen, S., Skrahina, A., Alikhanova, N., Mostofa Kamal, S. M., Barbova, A., Niemann, S., Groenheit, R., Dean, A. S., Zignol, M., Rigouts, L., Cirillo, D. M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2020
Sujets:
Mycobacteriology and Aerobic Actinomycetes
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587096/
https://ncbi.nlm.nih.gov/pubmed/32907992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01304-20
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