Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains

The role of mutations in genes associated with phenotypic resistance to bedaquiline (BDQ) and delamanid (DLM) in Mycobacterium tuberculosis complex (MTBc) strains is poorly characterized. A clear understanding of the genetic variants’ role is crucial to guide the development of molecular-based drug...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Battaglia, S., Spitaleri, A., Cabibbe, A. M., Meehan, C. J., Utpatel, C., Ismail, N., Tahseen, S., Skrahina, A., Alikhanova, N., Mostofa Kamal, S. M., Barbova, A., Niemann, S., Groenheit, R., Dean, A. S., Zignol, M., Rigouts, L., Cirillo, D. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587096/
https://ncbi.nlm.nih.gov/pubmed/32907992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01304-20
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