Characterization of Genomic Variants Associated with Resistance to Bedaquiline and Delamanid in Naive Mycobacterium tuberculosis Clinical Strains

The role of mutations in genes associated with phenotypic resistance to bedaquiline (BDQ) and delamanid (DLM) in Mycobacterium tuberculosis complex (MTBc) strains is poorly characterized. A clear understanding of the genetic variants’ role is crucial to guide the development of molecular-based drug...

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Veröffentlicht in:J Clin Microbiol
Hauptverfasser: Battaglia, S., Spitaleri, A., Cabibbe, A. M., Meehan, C. J., Utpatel, C., Ismail, N., Tahseen, S., Skrahina, A., Alikhanova, N., Mostofa Kamal, S. M., Barbova, A., Niemann, S., Groenheit, R., Dean, A. S., Zignol, M., Rigouts, L., Cirillo, D. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2020
Schlagworte:
Mycobacteriology and Aerobic Actinomycetes
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7587096/
https://ncbi.nlm.nih.gov/pubmed/32907992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01304-20
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