Application of Targeted Next-Generation Sequencing Assay on a Portable Sequencing Platform for Culture-Free Detection of Drug-Resistant Tuberculosis from Clinical Samples

Targeted next-generation sequencing (tNGS) has emerged as a comprehensive alternative to existing methods for drug susceptibility testing (DST) of Mycobacterium tuberculosis from patient sputum samples for clinical diagnosis of drug-resistant tuberculosis (DR-TB). However, the complexity of sequenci...

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Detalhes bibliográficos
Publicado no:J Clin Microbiol
Main Authors: Cabibbe, Andrea M., Spitaleri, Andrea, Battaglia, Simone, Colman, Rebecca E., Suresh, Anita, Uplekar, Swapna, Rodwell, Timothy C., Cirillo, Daniela M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7512157/
https://ncbi.nlm.nih.gov/pubmed/32727827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00632-20
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