7-Hydroxycoumarins Are Affinity-Based Fluorescent Probes for Competitive Binding Studies of Macrophage Migration Inhibitory Factor

[Image: see text] Macrophage migration inhibitory factor (MIF) is a cytokine with key roles in inflammation and cancer, which qualifies it as a potential drug target. Apart from its cytokine activity, MIF also harbors enzyme activity for keto–enol tautomerization. MIF enzymatic activity has been use...

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Publicado en:J Med Chem
Main Authors: Xiao, Zhangping, Chen, Deng, Song, Shanshan, van der Vlag, Ramon, van der Wouden, Petra E., van Merkerk, Ronald, Cool, Robbert H., Hirsch, Anna K. H., Melgert, Barbro N., Quax, Wim J., Poelarends, Gerrit J., Dekker, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2020
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586407/
https://ncbi.nlm.nih.gov/pubmed/32940040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c01160
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