Self-Adjuvanting Cancer Vaccines from Conjugation-Ready Lipid A Analogues and Synthetic Long Peptides

[Image: see text] Self-adjuvanting vaccines, wherein an antigenic peptide is covalently bound to an immunostimulating agent, have been shown to be promising tools for immunotherapy. Synthetic Toll-like receptor (TLR) ligands are ideal adjuvants for covalent linking to peptides or proteins. We here i...

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Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Reintjens, Niels R. M., Tondini, Elena, de Jong, Ana R., Meeuwenoord, Nico J., Chiodo, Fabrizio, Peterse, Evert, Overkleeft, Herman S., Filippov, Dmitri V., van der Marel, Gijsbert A., Ossendorp, Ferry, Codée, Jeroen D. C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7586330/
https://ncbi.nlm.nih.gov/pubmed/32960056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.0c00851
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