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Two in one: improving synthetic long peptide vaccines by combining antigen and adjuvant in one molecule
Aiming to increase the potency of synthetic long peptide (SLP)-based cancer vaccines, the Toll-like receptor 2 (TLR2) ligand Pam(3)CSK(4) was conjugated in a chemically defined fashion to SLPs harbouring both cytotoxic T lymphocyte (CTL) and T helper epitopes. We recently showed that these SLP-conju...
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| Publicat a: | Oncoimmunology |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292239/ https://ncbi.nlm.nih.gov/pubmed/25610736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.947892 |
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