Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines

Synthetic vaccines, based on antigenic peptides that comprise MHC−I and MHC‐II T‐cell epitopes expressed by tumors, show great promise for the immunotherapy of cancer. For optimal immunogenicity, the synthetic peptides (SPs) should be adjuvanted with suitable immunostimulatory additives. Previously,...

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Udgivet i:Chembiochem
Main Authors: van den Ende, Thomas C., Heuts, Jeroen M. M., Gential, Geoffroy P. P., Visser, Marten, van de Graaff, Michel J., Ho, Nataschja I., Jiskoot, Wim, Valentijn, A. Rob P. M., Meeuwenoord, Nico J., Overkleeft, Herman S., Codée, Jeroen D. C., van der Burg, Sjoerd H., Verdegaal, Els M. E., van der Marel, Gijsbert A., Ossendorp, Ferry, Filippov, Dmitri V.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Full Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049070/
https://ncbi.nlm.nih.gov/pubmed/33180981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000687
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