Simplified Monopalmitoyl Toll‐like Receptor 2 Ligand Mini‐UPam for Self‐Adjuvanting Neoantigen‐Based Synthetic Cancer Vaccines

Synthetic vaccines, based on antigenic peptides that comprise MHC−I and MHC‐II T‐cell epitopes expressed by tumors, show great promise for the immunotherapy of cancer. For optimal immunogenicity, the synthetic peptides (SPs) should be adjuvanted with suitable immunostimulatory additives. Previously,...

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Enregistré dans:
Détails bibliographiques
Publié dans:Chembiochem
Auteurs principaux: van den Ende, Thomas C., Heuts, Jeroen M. M., Gential, Geoffroy P. P., Visser, Marten, van de Graaff, Michel J., Ho, Nataschja I., Jiskoot, Wim, Valentijn, A. Rob P. M., Meeuwenoord, Nico J., Overkleeft, Herman S., Codée, Jeroen D. C., van der Burg, Sjoerd H., Verdegaal, Els M. E., van der Marel, Gijsbert A., Ossendorp, Ferry, Filippov, Dmitri V.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Full Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8049070/
https://ncbi.nlm.nih.gov/pubmed/33180981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000687
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