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BuGZ facilitates loading of spindle assembly checkpoint proteins to kinetochores in early mitosis
BuGZ is a kinetochore component that binds to and stabilizes Bub3, a key player in mitotic spindle assembly checkpoint signaling. Bub3 is required for kinetochore recruitment of Bub1 and BubR1, two proteins that have essential and distinct roles in the checkpoint. Both Bub1 and BubR1 localize to kin...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7586226/ https://ncbi.nlm.nih.gov/pubmed/32820050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013598 |
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