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BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment

During mitosis, the spindle assembly checkpoint (SAC) monitors the attachment of kinetochores (KTs) to the plus ends of spindle microtubules (MTs) and prevents anaphase onset until chromosomes are aligned and KTs are under proper tension. Here, we identify a SAC component, BuGZ/ZNF207, from an RNAi...

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書誌詳細
主要な著者: Toledo, Chad M., Herman, Jacob A., Olsen, Jonathan B., Ding, Yu, Corrin, Philip, Girard, Emily J., Olson, James M., Emili, Andrew, DeLuca, Jennifer G., Paddison, Patrick J.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995079/
https://ncbi.nlm.nih.gov/pubmed/24462187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.12.014
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