BuGZ is required for Bub3 stability, Bub1 kinetochore function, and chromosome alignment

During mitosis, the spindle assembly checkpoint (SAC) monitors the attachment of kinetochores (KTs) to the plus ends of spindle microtubules (MTs) and prevents anaphase onset until chromosomes are aligned and KTs are under proper tension. Here, we identify a SAC component, BuGZ/ZNF207, from an RNAi...

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Bibliografiske detaljer
Main Authors: Toledo, Chad M., Herman, Jacob A., Olsen, Jonathan B., Ding, Yu, Corrin, Philip, Girard, Emily J., Olson, James M., Emili, Andrew, DeLuca, Jennifer G., Paddison, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995079/
https://ncbi.nlm.nih.gov/pubmed/24462187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.12.014
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